Struggling NBA heavyweights square off when the Philadelphia 76ers battle the Los Angeles Lakers on Friday night. Philadelphia is coming off a 110-98 loss to the Los Angeles Clippers on Wednesday night, while the Lakers dropped a 131-114 decision that same night. Philadelphia will be without point guard Tyrese Maxey, out with a hamstring injury and center Joel Embiid (knee, suspension). Lakers power forward Anthony Davis (ankle) is listed as probable.

Tip-off from Crypto.com Arena in Los Angeles is set for 10 p.m. ET. The Lakers are 7.5-point favorites in the latest 76ers vs. Lakers odds from SportsLine consensus, while the over/under for total points scored is 224.5. The Lakers are -307 favorites on the money line, with Philly at +245 (see up-to-date odds for every game this week on our NBA odds page). 

Before you make any 76ers vs. Lakers picks, you NEED to see what the SportsLine Projection Model has to say.

The SportsLine Projection Model simulates every NBA game 10,000 times and has returned well over $10,000 in profit for $100 players on its top-rated NBA picks over the past six-plus seasons. The model enters Week 3 of the 2024-25 season on a sizzling 101-64 roll on all top-rated NBA picks dating back to last season, returning more than $3,000. Anyone following has seen HUGE returns!

The model has simulated 76ers vs. Lakers 10,000 times and the results are in. We can tell you that the model is leaning Over on the point total, and it also says one side of the spread hits in over 50% of simulations!

Who wins 76ers vs. Lakers, and which side of the spread is the better value? ... Join SportsLine right now to find out which side of the spread you should be all over, all from the model on a 101-64 roll on top-rated NBA picks!