Two teams with Super Bowl aspirations will collide when the San Francisco 49ers host the Dallas Cowboys on Sunday Night Football at Levi's Stadium. The 49ers (4-0) are one of only two remaining undefeated teams in the league. The Cowboys (3-1) bounced back from a shocking loss to Arizona with a 38-3 blowout of the Patriots.

Kickoff is at 8:20 p.m. ET. San Francisco is a 3.5-point favorite in the latest 49ers vs. Cowboys odds while the over/under for total points scored is 45. The 49ers are -184 favorites on the money line (risk $184 to win $100), while the Cowboys are +154 underdogs (risk $100 to win $154). Before you make any Cowboys vs. 49ers picks or NFL predictions, you need to see what the SportsLine Projection Model has to say.

The model, which simulates every NFL game 10,000 times, is up well over $7,000 for $100 players on top-rated NFL picks since its inception. The model enters Week 5 of the 2023 NFL season on an incredible 168-118 run on top-rated NFL picks that dates back to the 2017 season. It is also on a 22-10 roll on top-rated NFL picks since Week 7 of last season.

The model also ranked in the top 10 on NFLPickWatch four of the past six years on straight-up NFL picks and beat more than 94% of CBS Sports Football Pick'em players four times during that span. Anyone who has followed it is way up.

The model knows that San Francisco has arguably the best running back in the league, Christian McCaffrey. The rushing and receiving threat leads the NFL in rushing yards (459) and is tied for the league lead in total touchdowns (seven). He is just the third player in NFL history with 600-plus scrimmage yards and seven-plus touchdowns through four team games.

The model also has taken into account that the Cowboys' defense has been elite at pressuring the quarterback this season. Led by Micah Parsons, Dallas has the best pressure rate (55%) by any NFL team in its first four games of a season since at least 2017.

Now, the model has set its sights on 49ers vs. Cowboys. We can tell you the model is leaning Under the total, and it also says one side of the spread hits in almost 60% of simulations. You ABSOLUTELY need to see it before locking in any NFL picks.

So who wins Cowboys vs. 49ers on Sunday Night Football, and which side of the spread hits in almost 60% of simulations? Join SportsLine now to see which side of the 49ers vs. Cowboys spread to back, all from the model that's on an incredible 168-118 run on top-rated NFL picks!