Teams looking to complete a perfect preseason will meet on Thursday when the San Francisco 49ers battle the Houston Texans. Kickoff from NRG Stadium in Houston is slated for 8:15 p.m. ET. Both teams enter the game at 2-0 in the preseason. The 49ers are 3.5-point favorites in the latest 49ers vs. Texans odds from Caesars Sportsbook, while the Over-Under is 42. Before you make your 49ers vs. Texans picks or any other NFL predictions, you MUST see what San Francisco expert Tom Fornelli has to say. 

The CBS national writer went a profitable 29-16-1 in his last 46 NFL best bets. What's more, he has demonstrated a particularly sharp eye for the 49ers. In fact, Fornelli has gone a stunning 17-6 on picks involving San Francisco. Anyone who has followed him is WAY UP!

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San Francisco hopes to get a final look at its running backs position when they take on the Texans. Rookies Jordan Mason and Tyrion Davis-Price combined to gain 98 yards on 19 rushes in last Saturday's win over Minnesota, while second-year undrafted free agent JaMycal Hasty had three carries for 15 yards, including a score. Second-year running back Trey Sermon, who has been battling an ankle injury, had eight yards on five carries.

Houston coach Lovie Smith said the Texans' starters will see more action against the 49ers as the preseason concludes. That means projected starting quarterback Davis Mills will get a chance to show he can be the team's long-term solution at that position. Mills struggled in his first five drives against the Rams last week, but finished with a flourish. He wound up completing 10 of 17 passes for 96 yards (5.6 average) and one touchdown.        

For 49ers vs. Texans, we can tell you that Fornelli is leaning Under the total, but his much stronger play is on the spread. In fact, Fornelli has found a crucial X-factor that has him going BIG on one side! You ABSOLUTELY need to see it before locking in your own picks.

Who wins 49ers vs. Texans on Thursday night? And which crucial X-factor makes one side of the spread hit hard? ... Join SportsLine right now to see which side of the 49ers vs. Texans spread to jump on, all from the expert who's 17-6 on Niners picks! Use promo code EPIC to get a free two-week trial of SportsLine!

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