The two-time defending champion Kansas City Chiefs will try to reach their fifth Super Bowl in the last six years when they battle the Buffalo Bills in the 2025 AFC Championship Game on Sunday. It is the seventh consecutive year they have reached the AFC title game. The Bills (13-4), who are coming off a 27-25 win over the Baltimore Ravens in the divisional round, are 5-4 on the road this season. The Chiefs (15-2), who defeated the Houston Texans 23-14 on Saturday, are 9-0 at home.

Kickoff from GEHA Field at Arrowhead Stadium in Kansas City, Mo., is set for 6:30 p.m. ET on CBS and Paramount+. Kansas City is a 1.5-point favorite in the latest Bills vs. Chiefs odds, while the over/under for total points scored is 47.5. The Chiefs are -125 money-line favorites (risk $125 to win $100), while the Bills are +104 underdogs (risk $100 to win $104). 

Before making any Bills vs. Chiefs picks or predictions of your own, you NEED to see which side SportsLine NFL expert Mike Tierney is on. 

A veteran sportswriter whose work appears periodically in the New York Times and Los Angeles Times, Tierney has covered the NFL for decades and reported from seven Super Bowls. Tierney is 154-125-9 in the NFL the past two seasons, returning $1,586 to $100 players. In addition, he is an amazing 47-30-4 on his last 81 NFL picks in games involving the Bills, returning a whopping $1,435. Anyone who has followed him could be WAY UP!

Now, Tierney has locked in another confident against-the-spread pick for Bills vs. Chiefs on Sunday.

We can tell you he's leaning Under the point total, but he also knows a crucial X-factor makes one side of the spread a MUST-BACK! You ABSOLUTELY NEED to see what it is before locking in any picks of your own.

So who wins Bills vs. Chiefs on Sunday, and what X-factor makes one side of the spread hit HARD? ... Join SportsLine RIGHT NOW to see which side of the Bills vs. Chiefs spread hits HARD, all from the expert who is an amazing 47-30 on picks involving the Bills!