All four No. 1 seeds have made it to 2025's Final Four. That's far from usual, but Duke, Houston, Auburn and Florida have been the four best teams in the country all season. They were also the best teams in the 2025 NCAA Tournament, and they'll now battle on Saturday for a berth to the championship game. The action begins with Florida vs. Auburn at 6:09 p.m. ET, followed by Houston vs. Duke at 8:49 p.m., with both games on CBS.

Before you make wagers on the Final Four, you NEED to see what SportsLine expert Thomas Casale has to say. Casale has identified his top plays for Saturday's games. Be sure to check out his analysis before making any plays of your own.

What are SportsLine expert Thomas Casale's top picks for the Final Four? Join SportsLine right now to see the full breakdown, all from an expert who is on a 61-38 run over his last 99 college basketball picks for SportsLine!