A pair of struggling NFC East rivals square off when the New York Giants face the Dallas Cowboys in a Thanksgiving Day matchup in Arlington, Texas. Dallas snapped a five-game losing streak with a 34-26 win at Washington in Week 12, while New York dropped its sixth straight with a 30-7 loss to Tampa Bay. The Giants (2-9), who are 2-3 on the road this season, are 1-7 against NFC foes. The Cowboys (4-7), who are seeking their first home win after five losses, are 2-5 against conference opponents.

Kickoff from AT&T Stadium is set for 4:30 p.m. ET. Dallas has won the past six meetings, including a 20-15 win at New York in Week 4. Dallas is a 4-point favorite in the latest Giants vs. Cowboys odds, while the over/under for total points scored is set at 38. The Cowboys are the -203 money-line favorites (risk $203 to win $100), while the Giants are +169 underdogs (risk $100 to win $169).

Before making any Giants vs. Cowboys picks or NFL predictions of your own, you NEED to see which side SportsLine NFL expert Larry Hartstein is on. 

A former lead writer for Covers and The Linemakers, Hartstein combines a vast network of Vegas sources with an analytical approach he honed working for Pro Football Focus. He tied for 52nd place (out of 1,598 entries) in the 2022 Westgate Las Vegas SuperContest, going 53-34-3 ATS. Hartstein's weekly Vegas contest selections form the basis of his NFL best bets column, which is 79-48-2 (62.2%, +25.95 units) since its inception in 2022. He's also an INCREDIBLE 27-10 (+1580) on his last 37 NFL picks involving the Cowboys! Anyone who has followed him is way up.

Now, Hartstein has locked in another confident against-the-spread pick for Giants vs. Cowboys.

We can tell you he's leaning Under the point total, but he also knows a crucial X-factor makes one side of the spread a MUST-BACK! You ABSOLUTELY need to see what it is before locking in any picks of your own.

So who wins Giants vs. Cowboys on Thanksgiving Day, and what x-factor makes one side of the spread a MUST-BACK? ... Join SportsLine right now to see which side of the Giants vs. Cowboys spread hits HARD, all from the expert who is an AMAZING 27-10 on picks involving the Cowboys!