The No. 2 seed St. John's Red Storm (30-5) look to build on their Big East Tournament win as they take on the No. 15 seed Omaha Mavericks (22-12), the Summit League Champions, in the first round of the 2025 NCAA Tournament on Thursday on CBS and Paramount+.

Tip-off from Amica Mutual Pavilion in Providence, R.I. is set for 9:45 p.m. ET. The Red Storm are 19.5-point favorites in the latest Omaha vs. St. John's odds via SportsLine consensus, while the over/under for total points is 150.5.

Before making any Omaha vs. St. John's picks, check out the college basketball predictions from the SportsLine Projection Model.

The model simulates every Division 1 college basketball game 10,000 times. It enters the 2025 NCAA Tournament on a 228-166 roll (+2025) on all top-rated college basketball picks dating back to 2023. This model has also produced brackets that have beaten over 91% of CBS Sports entries in four of the last six tournaments and nailed 24 first-round upsets by double-digit seeds! Anyone following could have seen HUGE returns!

The model has simulated Omaha vs. St. John's 10,000 times and the results are in. We can tell you that the model is leaning Over, and it also says one side of the spread hits in over 50% of simulations!

So who wins Omaha vs. St. John's, and which side of the spread hits over 50% of the time? Join SportsLine right now to see which side of the spread you need to jump on, all from the computer model that is 228-166 (+2025) on top-rated college basketball pick and has nailed 24 double-digit upsets!