The PGA Tour season heads to the southeast region of the country with the 2022 Honda Classic set to tee off on Thursday, Feb. 24 at PGA National in Palm Beach Garden, Florida. The course is widely considered to be one of the toughest venues on the Tour and has gained notoriety for its brutal stretch on holes 15, 16, and 17. The total 2022 Honda Classic purse is $8 million, with $1.44 million going to the winner. The Honda Classic field lacks some star power, but household names like Brooks Koepka (20-1), Daniel Berger (16-1) and Tommy Fleetwood (22-1) will be on hand. Sungjae Im (14-1) is listed as the betting favorite in the latest Honda Classic odds from Caesars Sportsbook. He is followed by Berger, Joaquin Niemann (18-1), Koepka, and Louis Oosthuizen (22-1). Defending champion Matt Jones is listed at 33-1. All will likely be popular Honda Classic one and done picks. 

Before locking in your own 2022 Honda Classic one and done picks, you NEED to see what Daily Fantasy Sports pro Mike McClure has to say.

The One and Done format is growing in popularity. It has several noticeable similarities to NFL Survivor pools, with the main difference being entries are not eliminated with a bad week. Players pick one golfer per week and earn points based on their selected golfer's prize money for that tournament. Golfers can only be used once per season, and the point format makes nailing majors and big money tournaments critical.

McClure is a DFS legend with nearly $2 million in career winnings, and he's been RED-HOT on his PGA picks dating back to the PGA Tour restart in June of 2020. McClure uses his proprietary simulation model to analyze the field and crush his golf picks.

Two weeks ago at the Waste Management Phoenix Open, McClure's top three One and Done picks were Xander Schaffele, Brooks Koepka, and Louis Oosthuizen. Schauffele and Koepka finished T-3, one stroke behind the leaders, which was good for $434,600 each. Oosthuizen finished T-14, and won $133,250.

Three weeks ago, at the AT&T Pebble Beach Pro-Am, McClure was all over Matthew Fitzpatrick. The 27-year-old went out and shot 14-under par for the tournament, finishing in a tie for sixth place, taking home $293,625.

Four weeks ago at the Farmers Insurance Open, McClure's top pick was 25-year-old Will Zalatoris. The result: Zalatoris finished in sole possession of second place, taking home $915,600. While he came up short against eventual winner Luke List in a one-hole playoff, Zalatoris' performance at Torrey Pines was HUGE for one and done players.

At The American Express, McClure was all over Patrick Cantlay and Sungjae Im, who finished 9th ($222,300) and T-11 ($184,300), respectively. 

At the Sony Open 2022, McClure's model listed Hideki Matsuyama among the top contenders. The reigning Masters champion went out and overcame a five-stroke deficit on the back nine of the final round to notch his eighth career PGA Tour victory.

At the 2022 Sentry Tournament of Champions, McClure included Jon Rahm and Daniel Berger among his top PGA picks. The result: Rahm came in second with a score of 33-under par, while Berger secured a top-five finish with a score of 25-under par. Anybody that included them in their one and done picks is in great shape. 

At the 2021 World Wide Technology Championship at Mayakoba in November, the model was all over Viktor Hovland (18-1) winning his third PGA Tour title. At the 2021 Open Championship, McClure's best bets included Collin Morikawa winning outright even though he was listed as a massive 40-1 long shot. In addition, McClure's model was all over Jon Rahm's (10-1) first career major championship victory at the 2021 U.S. Open. 

McClure's model is up nearly $10,000 on its best bets since the restart, nailing tournament after tournament. Anyone who has followed it has seen MASSIVE returns, and anyone tailing his one and done picks should be in great shape. 

Now, McClure has set his sights on the 2022 Honda Classic and just revealed his optimal One and Done picks. They are a must-see for any player looking for an edge in their One and Done pool.

We can tell you that one of McClure's favorite Honda Classic Open One and Done picks is Tommy Fleetwood, who is currently listed at 22-1 to win the tournament at Caesars. Fleetwood, currently ranked No. 44 in the Official World Golf Rankings, is making his first appearance of the PGA Tour season. The 31-year-old has established himself as one of the premier golfers in the world, and is a definite threat to win any tournament he enters. He is coming off a T-7 finish at the Alfred Dunhill Links Championship on the European Tour, and McClure likes chances at notching his first outright win of the year.  With the talent in the Honda Classic field, it's very possible that Fleetwood will be an under-the-radar One and Done pick this week at PGA National.

McClure is also targeting another One and Done sleeper who's listed at 20-1 in the 2022 Honda Classic odds and is primed to blow up this week, giving you a HUGE return! Picks like these could be the difference between winning your One and Done pool or going home with nothing. You ABSOLUTELY need to see who it is before locking in your pick.

So what are the top One and Done picks for the 2022 Honda Classic? And which under-the-radar golfers offer HUGE One and Done value? ... Join SportsLine here to see the top 2022 Honda Classic One and Done picks, all from the expert who's made nearly $2 million in daily Fantasy sports!