Two of the greatest men's tennis players of all-time -- Rafael Nadal and Novak Djokovic -- collide in a blockbuster quarterfinal match on Tuesday at the 2022 French Open at Roland Garros in Paris. Nadal owns 21 career grand slam titles, the most of all time. Djokovic is tied for second with Roger Federer, with 20. For Tuesday Djokovic is a -250 favorite (risk $250 to win $100) in the latest Djokovic vs. Nadal odds from Caesars Sportsbook, while Nadal is a +190 underdog. The over/under for total games is 36.5. The match will not begin before 2:45 p.m. ET.

Before you lock in any 2022 French Open men's quarterfinals picks or Nadal vs. Djokovic props, you MUST see whom Sean Calvert is backing.

Calvert is the famed handicapper who called Stan Wawrinka winning the 2014 Australian Open at 60-1 -- the last Australian title won by someone other than Djokovic or Federer. In 2019, Calvert took down a huge score on Dominic Thiem winning Indian Wells at 80-1, among many stunning calls.

Now, Calvert has released best bets for the Djokovic vs. Nadal. We can tell you that he's leaning Under 36.5 total games (+100), but he has two even stronger plays, including a bet that returns almost 2-1! You ABSOLUTELY need to see all of Calvert's picks and analysis of the 2022 French Open before you bet.

So who wins Nadal vs. Djokovic? And which plus-money wager could lead to a HUGE return? ... Join SportsLine right now to see Sean Calvert's top 2022 French Open quarterfinal picks, all from the acclaimed expert who called Stan Wawrinka winning the 2014 Australian Open at 60-1!