Six-seeded Rafael Nadal continues his quest for an unprecedented 21st men's grand slam singles title when he faces No. 14 seed Denis Shapovalov in the 2022 Australian Open men's quarterfinals on Monday at 10:30 p.m. ET. Nadal is a -300 favorite (risk $300 to win $100) in the latest 2022 Australian Open odds from Caesars Sportsbook, while Shapovalov is a +210 underdog.

Before you lock in any 2022 Australian Open men's quarterfinals picks or props, you MUST see who Sean Calvert is backing.

Calvert is the famed handicapper who called Stan Wawrinka winning the 2014 Australian Open at 60-1 -- the last Australian title won by someone other than Djokovic or Roger Federer. In 2019, Calvert took down a huge score on Dominic Thiem winning Indian Wells at 80-1, among many stunning calls. 

And in 2021, he nailed both of his bets for the Wimbledon men's singles final: Djokovic to beat Matteo Berrettini three sets to one (+275) and Djokovic to win and both players to win a set (+130). Anyone following his picks is WAY up.

Now, Calvert has released best bets for the Nadal vs. Shapovalov, including a STRONG play on the outright winner and other props that could bring HUGE returns. You ABSOLUTELY need to see all of Calvert's picks and analysis of the 2022 Australian Open before you lock in any plays of your own.

So who wins Nadal vs. Shapovalov? And which pick could lead to a HUGE return? ... Join SportsLine right now to see Sean Calvert's top 2022 Australian Open quarterfinal picks, all from the acclaimed expert who called Stan Wawrinka winning the 2014 Australian Open at 60-1!