Division rivals will face off when the Los Angeles Rams host the San Francisco 49ers in the 2022 NFC Championship Game on Sunday. Kickoff in Los Angeles is set for 6:30 p.m. ET. The Rams are favored by 3.5 points in the latest 49ers vs. Rams odds from Caesars Sportsbook, while the over-under is 45.5.

Before you make any 49ers vs. Rams picks or any other NFL predictions, you NEED to see which side SportsLine NFL expert is on. 

Roberts has worked in the Las Vegas sportsbook industry for 20-plus years, including a 13-year run as Station Casinos' book director. He is 10-6 against the spread in his last 16 NFL picks, for a profit of $345. 

In addition, Roberts has gone an astounding 10-1 in his last 11 picks involving San Francisco. Anyone who has followed him is way up.

San Francisco averages more than 375 yards per game on offense, scoring 25.1 points per game in the process. The 49ers are No. 2 in the NFL in yards per attempt at 8.6. San Francisco moves the ball well on the ground, averaging 127.4 yards per game, and the defense is also potent. In fact, San Francisco is No. 3 in total defense and No. 6 in pass defense.

Los Angeles excels on both sides of the ball. The Rams finished with 50 sacks this season, a top-three mark, and were in the top 10 in turnovers created. The Rams are also in the top five in passer rating allowed and passing touchdowns allowed while holding opponents to 103.2 rushing yards per game. On offense, the Rams average more than 27 points per game and are top-10 in total offense.

Now, Roberts has locked in another confident against the spread pick for 49ers vs. Rams. We can tell you he's leaning under, but he knows a crucial X-factor makes one side of the spread a MUST-BACK! You ABSOLUTELY need to see what it is before locking in any picks of your own.

Who wins 49ers vs. Rams in the 2022 NFC Championship Game? And what critical X-factor makes one side of the spread a must-back? ... Join SportsLine right now to see which side of the 49ers vs. Rams spread to jump on, all from the expert who's an outstanding 10-1 on San Francisco picks!