San Francisco
Buffalo
San Francisco
| PASSING | CP/ATT | YD | TD | INT | FUML | FP | |
| B. Purdy | Brock Purdy | 20/30 | 233 | 1.29 | 0.71 | 0.15 | 18.72 |
| RUSHING | RUSH | YD | TD | YPC | FUML | FP | |
| C. McCaffrey | Christian McCaffrey | 15.0 | 76 | 0.35 | 5.1 | 0.14 | 14.58 |
| J. Mason | Jordan Mason | 4.6 | 24 | 0.08 | 5.2 | 0.03 | 3.29 |
| B. Purdy | Brock Purdy | 4.0 | 19 | 0.19 | 4.8 | 0.15 | 18.72 |
| RECEIVING | REC | YD | TD | YPR | FUML | FP | |
| J. Jennings | Jauan Jennings | 5.3 | 66 | 0.32 | 12.4 | 0.02 | 8.51 |
| G. Kittle | George Kittle | 4.9 | 60 | 0.63 | 12.2 | 0.02 | 9.89 |
| D. Samuel | Deebo Samuel | 3.9 | 51 | 0.18 | 13.1 | 0.04 | 7.89 |
| C. McCaffrey | Christian McCaffrey | 4.5 | 38 | 0.20 | 8.4 | 0.14 | 14.58 |
| R. Pearsall | Ricky Pearsall | 2.3 | 31 | 0.17 | 13.5 | 0.07 | 4.41 |
| K. Juszczyk | Kyle Juszczyk | 1.6 | 14 | 0.04 | 8.6 | 0.01 | 2.18 |
| DEF-ST | SACK | INT | FREC | FP | PA | Defensive TDs | |
| S. DST | SF DST | 1.54 | 0.72 | 0.57 | 7.18 | 26 | 0.11 |
PLAYERS LISTED AS OUT OR DOUBTFUL:Christian McCaffrey, Jordan Mason, Brandon Aiyuk, Elijah Mitchell, Talanoa Hufanga, Deommodore Lenoir, Nick Bosa, Dre Greenlaw, Drake Jackson, Javon Hargrave, Ambry Thomas, Demetrius Flannigan-Fowles, Kevin Givens, Jordan Elliott, Curtis Robinson, Tatum Bethune *Questionable players are included in the projection. | |||||||
San Francisco players
| PASSING |
| Brock Purdy |
| RUSHING |
| Christian McCaffrey |
| Jordan Mason |
| Brock Purdy |
| RECEIVING |
| Jauan Jennings |
| George Kittle |
| Deebo Samuel |
| Christian McCaffrey |
| Ricky Pearsall |
| Kyle Juszczyk |
| DEF-ST |
| SF DST |
| CP/ATT | YD | TD | INT | FUML | FP |
| 20/30 | 233 | 1.29 | 0.71 | 0.15 | 18.72 |
| RUSH | YD | TD | YPC | FUML | FP |
| 15.0 | 76 | 0.35 | 5.1 | 0.14 | 14.58 |
| 4.6 | 24 | 0.08 | 5.2 | 0.03 | 3.29 |
| 4.0 | 19 | 0.19 | 4.8 | 0.15 | 18.72 |
| REC | YD | TD | YPR | FUML | FP |
| 5.3 | 66 | 0.32 | 12.4 | 0.02 | 8.51 |
| 4.9 | 60 | 0.63 | 12.2 | 0.02 | 9.89 |
| 3.9 | 51 | 0.18 | 13.1 | 0.04 | 7.89 |
| 4.5 | 38 | 0.20 | 8.4 | 0.14 | 14.58 |
| 2.3 | 31 | 0.17 | 13.5 | 0.07 | 4.41 |
| 1.6 | 14 | 0.04 | 8.6 | 0.01 | 2.18 |
| SACK | INT | FREC | FP | PA | Defensive TDs |
| 1.54 | 0.72 | 0.57 | 7.18 | 26 | 0.11 |
PLAYERS LISTED AS OUT OR DOUBTFUL:
Christian McCaffrey, Jordan Mason, Brandon Aiyuk, Elijah Mitchell, Talanoa Hufanga, Deommodore Lenoir, Nick Bosa, Dre Greenlaw, Drake Jackson, Javon Hargrave, Ambry Thomas, Demetrius Flannigan-Fowles, Kevin Givens, Jordan Elliott, Curtis Robinson, Tatum Bethune
*Questionable players are included in the projection.