The Xavier Musketeers will take on the Southern Jaguars at 7 p.m. ET on Tuesday at Cintas Center. Xavier is riding a three-game winning streak following an 80-77 win at Cincinnati on Saturday. The Musketeers are favored by 21 points in the latest Xavier vs. Southern odds from Caesars Sportsbook, while the over/under is set at 154. 

Before you make any Southern vs. Xavier picks and predictions, you'll want to see what the SportsLine Projection Model is saying.

The SportsLine Projection Model simulates every Division I college basketball game 10,000 times. The model enters Week 6 of the 2022-23 college basketball season on a strong 17-10 roll on all-top rated CBB picks, returning almost $300. Anybody who has followed it has seen profitable returns!

Now, it has simulated Xavier vs. Southern 10,000 times and the results are in. We can tell you that the model is leaning Under on the point total, and it's also generated a point-spread pick that is hitting in almost 70% of simulations. You absolutely need to see it before locking in your own picks.

So who wins Xavier vs. Southern? And which side of the spread is a must-back? Join SportsLine right now to see which side of the spread you need to jump on, all from the computer model that has crushed its college basketball picks... If you're already a member, see the picks below!