The Wyoming Cowboys will take on the Tulsa Golden Hurricane at 3:30 p.m. ET on Saturday at Jonah Field at War Memorial Stadium. Wyoming is looking to bounce back from a season-opening loss to Illinois in Week 0, while Tulsa is getting set for its first game of the campaign. The Golden Hurricane are favored by 6.5 points in the latest Wyoming vs. Tulsa odds from Caesars Sportsbook, and the over/under is set at 44. 

Before you make any Tulsa vs. Wyoming picks, you'll want to see the college football predictions from the SportsLine Projection Model.

The SportsLine Projection Model simulates every FBS college football game 10,000 times. Over the past six-plus years, the proprietary computer model has generated a stunning profit of almost $3,600 for $100 players on its top-rated college football picks against the spread. It enters Week 1 of the 2022 college football season on a 45-32 run on all top-rated college football side picks that dates back to 2021. Anyone who has followed it has seen huge returns.

Now, it has simulated Wyoming vs. Tulsa 10,000 times and the results are in. We can tell you that the model is leaning Over, and it also says one side of the spread hits almost 60% of the time. You absolutely need to see it before locking in your own picks.

So who wins Wyoming vs. Tulsa? And which side of the spread hits almost 60% of the time? Join SportsLine right now to see which side of the spread you need to jump on, all from the computer model that has crushed its college football picks.