The Illinois Fighting Illini host the Wyoming Cowboys in a Week 0 contest in Champaign, Illinois at 4 p.m. ET on Saturday. Illinois is favored by 14 points at Caesars Sportsbook, while the over/under is set at 43 (see up-to-date odds for every game this week on our college football odds page). 

Before making any Wyoming vs. Illinois picks, you NEED to check out the college football predictions from the SportsLine Projection Model.

The SportsLine Projection Model simulates every FBS college football game 10,000 times. Over the past six years, the proprietary computer model has generated a stunning profit of almost $3,600 for $100 players on its top-rated college football picks against the spread. It also finished the 2021-22 college football season on a 43-31 run on all top-rated college football side picks. Anyone who has followed it has seen HUGE returns.

The model knows Illinois owns a run-first offense. The Fighting Illini have a bunch of maulers on the offensive line with outstanding grit and strength. They averaged 173.6 rushing yards per game. Junior running back Chase Brown is the leading tailback for this unit with great vision and burst. He finished the 2021 campaign ranked third in the Big Ten in rushing yards (1,005). 

The model also knows Wyoming loves to pound the rock. In 2021, the Cowboys were second in the Mountain West in rushing yards per game (211.2). Junior tailback Titus Swen is hoping to take another step in his development. Last year, he logged 132 carries for 785 yards and a team-high seven scores. 

Now, it has set its sights on Wyoming vs. Illinois. We can tell you the model is leaning Over the total, and it also says one side of the spread hits in well over 60% of simulations! You ABSOLUTELY need to see it before locking in any college football picks.

So who wins Illinois vs. Wyoming? And which side of the spread hits well over 60% of the time? Join SportsLine now to find out, all from the model that has crushed its top-rated college football picks!