A Big 12 battle is on tap between the West Virginia Mountaineers and the No. 11 Iowa State Cyclones at 7 p.m. ET on Wednesday at WVU Coliseum. West Virginia is 14-9 overall and 10-3 at home, while the Cyclones are 16-6 overall and 2-5 on the road. The Mountaineers are favored by 3.5 points in the latest West Virginia vs. Iowa State odds from Caesars Sportsbook and the over/under is set at 135.5. Before you make any Iowa State vs. West Virginia picks and predictions, you'll want to see what the SportsLine Projection Model is saying.

The SportsLine Projection Model simulates every Division I college basketball game 10,000 times. The model enters Week 13 of the season 50-29 on all top-rated college basketball picks, returning more than $1,200 for $100 players. Anybody who has followed it has seen huge returns.

Now, it has simulated West Virginia vs. Iowa State 10,000 times and the results are in. We can tell you that the model is leaning Over and it's also generated a point-spread pick that is hitting in well over 50% of simulations. You absolutely need to see it before locking in your own picks.

So who wins West Virginia vs. Iowa State? And which side of the spread is a must-back? Join SportsLine right now to see which side of the spread you need to jump on, all from the computer model that has crushed its college basketball picks... If you're already a member, see the picks below!