Wake Forest will face Virginia in an ACC matchup on Friday at Scott Stadium in Charlottesville, Virginia. Kickoff is 7:30 p.m. ET. The Cavaliers are 3.5-point favorites in the latest Wake Forest vs. Virginia odds from Caesars Sportsbook, while the Over/Under for total points scored is 70. (See the latest college football lines for all of this week's games on our college football odds page.)

Before you make any Wake Forest vs. Virginia picks and college football predictions, you need to see what the SportsLine Projection Model has to say.

The SportsLine Projection Model simulates every FBS college football game 10,000 times. Over the past five-plus years, the proprietary computer model has generated a stunning profit of almost $3,000 for $100 players on its top-rated college football picks against the spread. It also enters Week 4 of the 2021 season on a 72-58 run on all top-rated college football picks. Anyone who has followed it has seen HUGE returns.

The Demon Deacons are off to a strong start. They extended their winning streak to three games last weekend with a 35-14 win against Florida State and have beaten opposing teams by an average of 26 points. Wake Forest's defense forced six turnovers against the Seminoles and have tallied nine takeaways on the year. Protecting the pigskin should be a point of emphasis for the home team's explosive offense.

The Cavaliers lost to No. 21 North Carolina last week but are averaging more than 41 points per game. Virginia quarterback Brennan Armstrong has thrown for 1,298 yards and 11 touchdowns with two interceptions and fuels the favorite's aerial attack. Only one signal-caller has racked up more yardage through the air in 2021. Containing the gunslinger could be challenging for the Demon Deacons.

Now the model has simulated Wake Forest vs. Virginia 10,000 times, and the results are in. We can tell you that the model is leaning Under on the total, and it has generated a point-spread pick that is hitting in over 60 percent of simulations. You absolutely need to see it before locking in your own picks.

Who wins the battle between Wake Forest and Virginia? And which side of the spread hits in over 60 percent of simulations? ... Join SportsLine right now to see which side of the Wake Forest vs. Virginia spread you need to jump on Friday, all from the computer model that has crushed its college football picks!