The Virginia Tech Hokies and Boston College Eagles will be trying to string some wins together when they meet Friday night in Chestnut Hill, Mass., in an Atlantic Coast Conference matchup. Kickoff is set for 7:30 p.m. ET at BC Alumni Stadium. 

The Hokies are 2.5-point favorites in the latest Virginia Tech vs. Boston College odds from Caesars Sportsbook, while the over-under for total points scored is 50. (See the latest college football lines for all of this week's games on our college football odds page.)

Before you consider your Boston College vs. Virginia Tech picks or college football predictions, you need to see what the SportsLine Projection Model has to say.

The SportsLine Projection Model simulates every FBS college football game 10,000 times. Over the past five-plus years, the proprietary computer model has generated a stunning profit of almost $3,700 for $100 players on its top-rated college football picks against the spread. It also enters Week 10 of the 2021 season on a 28-15 run on all top-rated college football side picks. Anyone who has followed it has seen HUGE returns.

The Hokies (4-4, 2-2) are a game behind Pitt in the Coastal Division and lost to the Panthers 28-7 three weeks ago. They snapped a three-game losing streak with a 26-17 win at Georgia Tech last weekend and  are 9-4 in the past 13 meetings with BC. The offense is powered by running backs Raheem Blackshear and Malachi Thomas, who have combined for 660 yards and seven TDs. But receiver Tre Turner (602 yards, 17.7 per catch) is a dangerous target for quarterback Braxton Burmeister (1,485 yards, nine TDs).                

BC (4-4, 0-4) has lost four straight after a promising start and counts on a defense that gives up less than 21 points per game and ranks 11th in the nation against the pass (174 yards per game). Running back Pat Garwo (689 yards, five TDs) is the focal point of the offense as quarterback Dennis Grosel (six TDs, seven INTs) has struggled. The Hokies allow 178 rushing yards  per game (95th in FBS). But wideout Zay Flowers (511 yards, 14.6 per catch) and tight end Trae Berry (288, 16 per reception) give Grosel strong options.

The model has simulated Virginia Tech vs. Boston College 10,000 times, and the results are in. We can tell you that the model is leaning Over on the total, and it also says that one side of the spread is hitting in well over 50 percent of simulations. You absolutely need to see it before locking in your own picks.

Who wins the Virginia Tech vs. Boston College ACC matchup on Friday? And which side of the spread hits in well over 50 percent of simulations? ... Join SportsLine right now to see which side of the Boston College vs. Virginia Tech spread you need to jump on Friday, all from the computer model on a 28-15 run on its top-rated college football side picks!