A Pac-12 battle is on tap between the Arizona State Sun Devils and the USC Trojans at 10:30 p.m. ET on Saturday, November 6 at Sun Devil Stadium, Frank Kush Field. ASU is 5-3 overall and 4-1 at home, while USC is 4-4 overall and 2-1 on the road. 

The Sun Devils are favored by eight points in the latest Arizona State vs. USC odds from Caesars Sportsbook, and the over-under is set at 59.5. Before you make any USC vs. Arizona State picks, you'll want to see the college football predictions from the SportsLine Projection Model.

The SportsLine Projection Model simulates every FBS college football game 10,000 times. Over the past five-plus years, the proprietary computer model has generated a stunning profit of almost $3,700 for $100 players on its top-rated college football picks against the spread. It also enters Week 10 of the 2021 season on a 28-15 run on all top-rated college football side picks. Anyone who has followed it has seen HUGE returns.

Now, it has simulated Arizona State vs. USC 10,000 times and the results are in. We can tell you that the model is leaning over on the point total, and it's also generated a point-spread pick that is hitting in almost 60 percent of simulations. You absolutely need to see it before locking in your own picks.

So who wins Arizona State vs. USC? And which side of the spread is a must-back? Join SportsLine right now to see which side of the spread you need to jump on, all from the computer model that has crushed its college football picks... If you're already a member, see the picks below!