Saturday's UFC Fight Night main event features top-five heavyweights, as second-ranked Curtis Blaydes takes on fourth-rated Derrick Lewis. The main UFC fight card is scheduled for 8 p.m. ET. Blaydes is a -380 favorite (risk $380 to win $100), while Lewis is a +300 underdog (risk $100 to win $300) in the latest Blaydes vs. Lewis odds from William Hill Sportsbook.

Before making any UFC Fight Night: Blaydes vs. Lewis picks of your own, you NEED to see the latest MMA predictions from SportsLine MMA analyst Kyle Marley.

Over the past 24 months, $100 bettors who have followed Marley's picks are up more than $22,000. The accomplished MMA analyst has seen memorable run in 2020 carry over into 2021. He has now nailed 27 of his last 37 UFC main-event picks, a stretch that included a streak of five consecutive underdogs!

At UFC 258 last weekend, Marley told SportsLine members to back Kamaru Usman (-270) against Gilbert Burns (+230) in the third title defense for Usman of his welterweight title. He delivered a third-round stoppage to give Marley's followers another winner. Anyone who has followed Marley is WAY UP! 

This week for UFC Fight Night: Blaydes vs. Lewis, we can tell you Marley is backing Charles Rosa (-185) to earn a submission victory over Darrick Minner (+165) in a matchup of featherweight contenders on the main card. He's also backing one fighter to get "a dominant, early, ground-and-pound finish!" You ABSOLUTELY need to see Marley's picks before making any of your own.

Who wins Blaydes vs. Lewis and every bout on the UFC Fight Night card? And which fighter is a must-back? ... Join SportsLine right now to see which fighters you need to be all over Saturday, all from the expert who's up more than $22,000 on MMA picks and has nailed a whopping 27 of the last 37 main events!