The UFC welterweight title will be on the line Saturday when champion and top-ranked Kamaru Usman goes into the Octagon to face top contender Leon Edwards. The main UFC 278 fight card is set for 10 p.m. ET from Vivint Arena in Salt Lake City. Usman is a -360 favorite (risk $380 to win $100), while Edwards is a +300 underdog (risk $100 to win $300) in the latest UFC 278: Usman vs. Edwards 2 odds from Caesars Sportsbook.

Before finalizing any UFC 278: Usman vs. Edwards 2 picks, you NEED to see the latest MMA predictions from SportsLine MMA analyst Kyle Marley. Over the past three-plus years, $100 bettors who have followed Marley's picks are up more than $13,000! 

The accomplished MMA analyst has provided consistent winners for SportsLine members for the past three-plus years. His accomplishments include hitting five consecutive main-event underdog winners in 2020 following the UFC's brief pause in action because of the pandemic. Anyone who has followed Marley is WAY UP!

This week at UFC 278: Usman vs. Edwards 2, we can tell you Marley is backing Wu Yanan (+100) to get past Lucie Pudilova (-120) in a women's bantamweight matchup on the main card.

Marley also has strong picks for Usman vs. Edwards 2 and every other bout on the UFC Fight Night card. He's also backing a fighter who "is a dangerous fighter" to emerge with a dominant victory! You MUST SEE his UFC 278 picks before making any of your own.

Who wins UFC 278: Usman vs. Edwards 2? And which fighter is a MUST-BACK? ... Join SportsLine right now to see which fighters you need to be all over Saturday, all from the expert who's up more than $13,000 on MMA picks!