Unbeaten Ciryl Gane and Derrick Lewis highlight a jam packed UFC 265 fight card that will take place on Saturday in Houston. The matches will be held at Toyota Center with a 10 p.m. ET start time to the main card. The interim UFC heavyweight championship will be one the line. Lewis, a former Legacy FC heavyweight champion, failed in his last opportunity to claim the heavyweight championship when he lost by submission to Daniel Cormier in November 2018 Gane is 9-0 since joining UFC in 2018.

There are countless Gane vs. Lewis prop bets from sportsbooks like Caesars Sportsbook. Prominent options include that the fight lasts five rounds at +150 and that Gane will win by TKO at +138. There is also a UFC prop bet on who wins each individual round in the main event.

Before making any picks for UFC 265: Gane vs. Lewis, you need to see the UFC predictions from SportsLine MMA expert Brandon Wise. He specializes in picking main-card fights for UFC, which has enabled him to be profitable every year! 

In fact, Wise called Israel Adesanya by decision at +140 and Brandon Moreno to win outright at +190 at UFC 263 earlier this summer. Wise went a perfect 5-0 at UFC 239 and was 4-1 at both UFC 245 and UFC 249.

He also nailed Khabib Nurmagomedov's destruction of Conor McGregor in 2018, Stipe Miocic's defeat of Daniel Cormier, Max Holloway's downfall in 2019 and Justin Gaethje's TKO victory over Tony Ferguson in May of last year.

Now, with UFC 265: Gane vs. Lewis fast approaching, Wise has carefully studied every main-card matchup and the available props and released his MMA predictions. Successfully parlaying his top picks would return more than 18-1!

For UFC 265, we can tell you Wise is backing Angela Hill to defeat Tecia Torres by decision (+180) in their women's strawweight bout.

Wise also has strong picks for Gane vs. Lewis and every other bout on the UFC 265 main card. He's also backing an underdog to win by TKO, disqualification or submission, netting any backer a big payday of well over 2-1. 

Who wins Gane vs. Lewis? And which props do you need to be all over for an 18-1 payday? ... Join SportsLine now to see which fighters you need to be all over at UFC 265 all from the accomplished MMA analyst who has been profitable for six straight years!