The Portland Trail Blazers open their 2024-25 NBA season by hosting the Golden State Warriors on Wednesday at Moda Center at the Rose Quarter. Portland finished last season with a 21-61 overall record, which was good for last place in the Western Conference. The Warriors finished 46-36, but missed the NBA Playoffs for the first time since 2021. 

Tip-off in Portland is at 10 p.m. ET. The Warriors are favored by 6 points in the latest Trail Blazers vs. Warriors odds, and the over/under is 222.5 points. Before locking in any Trail Blazers vs. Warriors picks, you'll want to see the NBA predictions and betting advice from the proven computer simulation model at SportsLine.

The SportsLine Projection Model simulates every NBA game 10,000 times and has returned well over $10,000 in profit for $100 players on its top-rated NBA picks over the past six seasons. The model ended the 2023-24 season on a sizzling 94-61 roll on all top-rated NBA picks, returning more than $2,800 in the process. Anyone following has seen HUGE returns!

The model has simulated Trail Blazers vs. Warriors 10,000 times and the results are in. We can tell you that the model is leaning Under on the point total, and it's also generated a point-spread pick that is hitting in almost 70% of simulations. You can only see the model's pick at SportsLine.

So who wins Trail Blazers vs. Warriors? And which side of the spread is a must-back? Join SportsLine right now to see which side of the spread you need to jump on, all from the computer model that has crushed its NBA picks.