The Tennessee Volunteers will take on the Pittsburgh Panthers at noon ET on Saturday at Neyland Stadium. The Volunteers are 1-0 overall and 1-0 at home, while Pitt is 1-0 overall and 0-0 on the road. Tennessee ended last year fifth in the SEC East Division, while the Panthers ended up fifth in the ACC Coastal Division. The Panthers are favored by four points in the latest Tennessee vs. Pittsburgh odds from Caesars Sportsbook, and the over-under is set at 56. 

Before making any Pittsburgh vs. Tennessee picks, you'll want to see the college football predictions from the SportsLine Projection Model.

The SportsLine Projection Model simulates every FBS college football game 10,000 times. Over the past five-plus years, the proprietary computer model has generated a stunning profit of over $3,500 for $100 players on its top-rated college football picks against the spread. It also enters Week 2 of the 2021 season on a 63-45 run on all top-rated college football picks. Anyone who has followed it has seen HUGE returns.

Now, it has simulated Tennessee vs. Pittsburgh 10,000 times and the results are in. We can tell you that the model is leaning Under, and it's also generated a point-spread pick that is hitting in well over 50 percent of simulations. You absolutely need to see it before locking in your own picks.

So who wins Tennessee vs. Pittsburgh? And which side of the spread is a must-back? Join SportsLine right now to see which side of the spread you need to jump on, all from the computer model that has crushed its college football picks. .. If you're already a member, see the picks below!