The Tennessee Volunteers will take on the Ole Miss Rebels at 7 p.m. ET on Wednesday at Thompson-Boling Arena. The Volunteers are 9-3 overall on the season, while the Rebels are 8-4 in 2021-22. The Volunteers are favored by 16.5 points in the latest Tennessee vs. Ole Miss odds from Caesars Sportsbook, and the over-under is set at 133.5. Before you make any Ole Miss vs. Tennessee picks and predictions, you'll want to see what the SportsLine Projection Model is saying.

The SportsLine Projection Model simulates every Division I college basketball game 10,000 times. Over the past five-plus years, the proprietary computer model has generated an impressive profit of almost $2,200 for $100 players on its top-rated college basketball picks against the spread. Anyone who has followed it has seen huge returns.

Now, it has simulated Tennessee vs. Ole Miss 10,000 times and the results are in. We can tell you that the model is leaning Over, and it's also generated a point-spread pick that is hitting in well over 60 percent of simulations. You absolutely need to see it before locking in your own picks.

So who wins Tennessee vs. Ole Miss? And which side of the spread is a must-back? Join SportsLine right now to see which side of the spread you need to jump on, all from the computer model that has crushed its college basketball picks... If you're already a member, see the picks below!