The Syracuse Orange will play their second home game in three days when they host the Canisius Golden Griffins during the first week of the college basketball season. Tipoff is set for 7 p.m. ET on Wednesday at JMA Wireless Dome. Syracuse is favored by 13.5 points in the latest Syracuse vs. Canisius odds, while the over/under is set at 149.5 points, per SportsLine consensus. 

Before entering any Canisius vs. Syracuse picks, you NEED to see the college basketball predictions from the model at SportsLine.

The model simulates every Division I college basketball game 10,000 times. It went 85-55 on all top-rated college basketball picks last season, returning more than $1,600 for $100 players. Anyone who followed it saw HUGE returns!                                                                                                                                                                                                                                                                                                                                                                                       The model has simulated Syracuse vs. Canisius 10,000 times and the results are in. We can tell you that the model is leaning Under, and it's also generated a point-spread pick that is hitting in well over 70% of simulations. You can only see the pick at SportsLine.

So who wins Syracuse vs. Canisius? And which side of the spread is hitting well over 70% of the time? Join SportsLine right now to see which side of the spread you need to jump on, all from the computer model that went 85-55 on its college basketball picks. If you're already a member, see the picks below!