The UTSA Roadrunners welcome the South Florida Bulls to the Alamodome in San Antonio for an American Athletic Conference showdown at 9 p.m. ET on Friday. For this matchup, SportsLine consensus lists the Roadrunners as 15.5-point favorites, while the over/under is 66.5 (see up-to-date odds for every game this week on our college football odds page). 

Before making any South Florida vs. UTSA picks, you NEED to check out the college football predictions from the SportsLine Projection Model.

The SportsLine Projection Model simulates every FBS college football game 10,000 times. Since its inception, it has generated a strong profit of well over $2,000 for $100 players on its top-rated college football picks against the spread. Anyone who has followed it has seen HUGE returns!

The model knows the Roadrunners are tough to beat at home and have won 20 of their last 22 home games. They are 22-3 (.880) at the Alamodome under coach Jeff Traylor, including 17-0 against league opponents. Helping power the offense is senior quarterback Frank Harris, who has completed 162 of 252 passes (64.3%) for 1,897 yards and 14 touchdowns. He has been intercepted six times, but has a rating of 141.1. Harris has also carried 63 times for 183 yards (2.9 average) and one TD.  

The model also knows freshman quarterback Byrum Brown is a big reason why the Bulls have already won four more games than they did all of last year. They are tied with Northwestern for the nation's biggest improvement over 2022. Brown has posted four 300-plus passing games this year, including two in a row. He is also the team's second-leading rusher, carrying 168 times for 659 yards (3.9 average) and nine TDs.

Now, it has set its sights on South Florida vs. UTSA. We can tell you the model is leaning Over the total, and it also says one side of the spread hits in well over 60% of simulations! You ABSOLUTELY need to see it before locking in any college football picks.

Who wins South Florida vs. UTSA? And which side of the spread hits in well over 60% of simulations? ... Join SportsLine right now to find out which side of the South Florida vs. UTSA spread you should be all over Friday, all from the model on a roll on college football picks!