The Philadelphia 76ers will take on the Chicago Bulls at 7 p.m. ET Wednesday at Wells Fargo Center. Philadelphia is 5-2 overall and 3-1 at home, while Chicago is 6-1 overall and 3-0 on the road. 

 Philadelphia is favored by two points in the latest Sixers vs. Bulls odds from Caesars Sportsbook, and the over-under is set at 215.5. Before you make any Bulls vs. Sixers picks and predictions, you'll want to see what the SportsLine Projection Model is saying.

The SportsLine Projection Model simulates every NBA game 10,000 times and has returned almost $9,000 in profit on its top-rated NBA picks over the past three-plus seasons. The model finished up almost $600 on its top-rated picks last season and entered Week 3 of the 2021-22 NBA season on a stunning 106-71 roll on top-rated NBA picks against the spread. Anyone following it has seen huge returns.

Now, it has simulated Sixers vs. Bulls 10,000 times and the results are in. We can tell you that the model is leaning Over, and it also has generated a pick that hits in over 50 percent of simulations. You absolutely need to see it before locking in your own picks.

So who wins Sixers vs. Bulls? And which side of the spread is a must-back? Join SportsLine right now to see which side of the spread you need to jump on, all from the computer model that has crushed its NBA picks... If you're already a member, see the picks below!