A first round 2022 NCAA Tournament matchup is set between No. 8 seed San Diego State and No. 9 seed Creighton at 7:27 p.m. ET on Thursday at Dickies Arena. The Aztecs are 23-8 overall, while Creighton is 22-11 overall. San Diego State finished in third place in the Mountain West; Creighton was fourth in the Big East. 

The Aztecs are favored by two points in the latest San Diego State vs. Creighton odds from Caesars Sportsbook, while the over-under is set at 121. Before you make any Creighton vs. San Diego State picks and predictions, you'll want to see what the SportsLine Projection Model is saying.

The SportsLine Projection Model simulates every Division I college basketball game 10,000 times. Over the past five-plus years, the proprietary computer model has generated an impressive profit of almost $1,500 for $100 players on its top-rated college basketball picks against the spread. Anyone who has followed it has seen huge returns.

Now, it has simulated San Diego State vs. Creighton 10,000 times and the results are in. We can tell you that the model is leaning Over, and it also says one side of the spread has ALL the value. You need to see it before locking in your own picks.

So who wins San Diego State vs. Creighton? And which side of the spread has ALL the value? Join SportsLine right now to see which side of the spread you need to jump on, all from the computer model that has crushed its college basketball picks.