The New Orleans Saints (2-4) and Arizona Cardinals (2-4) will clash on Thursday Night Football. Kickoff is set for 8:15 p.m. ET from State Farm Stadium. Arizona is a 2.5-point favorite in the latest Saints vs. Cardinals odds from Caesars Sportsbook, and the over/under for total points scored is 43.5. Before making any Saints vs. Cardinals picks of your own, you NEED to check out the NFL predictions from the SportsLine Projection Model.

The model, which simulates every NFL game 10,000 times, is up almost $7,000 for $100 players on top-rated NFL picks since its inception. The model enters Week 7 of the 2022 NFL season on an incredible 146-107 run on top-rated NFL picks that dates back to the 2017 season.

The model also ranked in the top 10 on NFLPickWatch four of the past six years on straight-up NFL picks and beat more than 94% of CBS Sports Football Pick'em players four times during that span. Anyone who has followed it is WAY UP.

The model knows Arizona quarterback Kyler Murray is a dynamic, dual-threat weapon. The 2019 first-overall pick has a big throwing arm and can easily air out the football. Murray is 12th in the NFL in passing yards (1,463) with six passing touchdowns and 233 rushing yards. 

The model also knows New Orleans running back Alvin Kamara has strong route-running skills and sure hands. Kamara is elusive in the open field and has the quickness to break away from defenders. The five-time Pro Bowler has 66 carries for 302 yards while snagging 17 passes for 135 receiving yards.

Now, the model has set its sights on Saints vs. Cardinals on Thursday Night Football. We can tell you the model is leaning Over the total, and it also says one side of the spread has ALL the value! You ABSOLUTELY need to see it before locking in any NFL picks.

So who wins Saints vs. Cardinals on Thursday Night Football? And which side of the spread has ALL the value? Join SportsLine now to see which side of the Saints vs. Cardinals spread to back, all from the model that's an amazing 146-107 on NFL picks!