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Royals vs. Guardians odds, picks: Advanced computer MLB model releases selections for Wednesday matchup

SportsLine's projection model generated selections for Wednesday's matchup between the Kansas City Royals and the Cleveland Guardians

The Kansas City Royals face the Cleveland Guardians in a matinee American League contest at 1:10 p.m. ET on Wednesday. Cleveland is listed as a -140 favorite (risk $140 to win $100) at Caesars Sportsbook, while the Over-Under is set at 9 (see up-to-date odds for every game this week on our MLB odds page). Before making any Royals vs. Guardians picks, you NEED to check out the MLB predictions from the SportsLine Projection Model.

The SportsLine Projection Model simulates every MLB game 10,000 times and it is off to a strong start to the 2022 season. It's on a 48-31 roll on top-rated MLB money-line picks through eight weeks, returning over $1,100 for $100 players. Anyone following it has seen HUGE returns!

The model knows the Royals have an effective starting pitcher in Brad Keller. He has a 3.95 ERA in nine starts this season, walking only 2.5 batters per nine innings. Keller also has a 50.7 percent career ground ball rate, and he has dominated Cleveland. In 10 career appearances against the Guardians, Keller has an outstanding 1.71 ERA with strong peripherals. 

The model also knows the Guardians have clear offensive strengths. Cleveland leads the AL in triples with 13, and the Guardians have the fewest strikeouts (324) in the league. The Guardians are also in the top five in batting average and above the median in stolen bases. In addition, Cleveland is facing a Kansas City bullpen that ranks dead-last in the AL in ERA and walk rate this season.

Now, it has set its sights on Royals vs. Guardians. We can tell you the model is leaning under the total, and it also says one team has all the value! You ABSOLUTELY need to see it before locking in any MLB picks.

Who wins Royals vs. Guardians? And which team has all the value on the money line? ... Join SportsLine right now to find out which side of the Royals vs. Guardians matchup you should be all over Thursday, all from the model on a roll on MLB picks!

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SportsLine Staff
SportsLine Staff

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