The Los Angeles Rams (1-2) travel east to take on the Indianapolis Colts (2-1) at Lucas Oil Stadium in a cross-conference NFL Week 4 matchup on Sunday. The Rams are aiming to bounce back from a 19-16 loss to the Cincinnati Bengals on Monday Night Football, while the Colts are looking to stay hot after notching a 22-19 overtime win over the Baltimore Ravens in Week 3.

Kickoff at Lucas Oil Stadium is scheduled for 1 p.m. ET. Indianapolis is a 1-point favorite and the over/under for total points scored is 45 in the latest Rams vs. Colts odds. Before making any Colts vs. Rams picks of your own, you NEED to check out the NFL predictions from the SportsLine Projection Model.

The model, which simulates every NFL game 10,000 times, is up more than $7,000 for $100 players on top-rated NFL picks since its inception. The model enters Week 4 of the 2023 NFL season on an incredible 167-117 run on top-rated NFL picks that dates back to the 2017 season. It is also on a 21-9 roll on top-rated NFL picks since Week 7 of last season.

The model also ranked in the top 10 on NFLPickWatch four of the past six years on straight-up NFL picks and beat more than 94% of CBS Sports Football Pick'em players four times during that span. Anyone who has followed it is WAY UP.

Now, the model has set its sights on Rams vs. Colts. We can tell you the model is leaning Under on the point total, and it also says one side of the spread has all the value! You ABSOLUTELY need to see it before locking in any NFL picks.

Who wins Rams vs. Colts in Week 4 of the 2023 NFL season, and which side of the spread is the better value? ... Join SportsLine right now to find out which side of the Colts vs. Rams spread is a MUST-BACK, all from the model on a 167-117 roll on NFL picks!