The Purdue Boilermakers (1-1) and the Syracuse Orange (2-0) clash on Sunday afternoon at noon ET. Syracuse is listed at -1.5 in the latest Syracuse vs. Purdue odds from Caesars Sportsbook, while the over/under is set at 60 (see up-to-date odds for every game this week on our college football odds page). 

Before making any Purdue vs. Syracuse picks, you NEED to check out the college football predictions from the SportsLine Projection Model.

The SportsLine Projection Model simulates every FBS college football game 10,000 times. Over the past six-plus years, the proprietary computer model has generated a stunning profit of almost $3,400 for $100 players on its top-rated college football picks against the spread. It enters Week 3 of the 2022 college football season on a 50-41 run on all top-rated college football spread and money-line picks that dates back to 2021. Anyone who has followed it has seen huge returns.

The model knows Purdue senior receiver Charlie Jones has opened the 2022 campaign with outstanding performances. Jones is a smooth route runner who owns secure hands. He plucks the ball out of the air and has the ability to track down deep passes. The Illinois native is leading the team in catches (21), receiving yards (286) and touchdowns (4). 

The model also knows Syracuse junior quarterback Garrett Shrader is a confident signal-caller. Shrader has been accurate and poised under center. The North Carolina native completes 79% of his throws for 523 yards with five passing touchdowns. He's also athletic enough to make plays with his legs, rushing for 118 yards with three scores. 

Now, it has set its sights on Purdue vs. Syracuse. We can tell you the model is leaning Under the total, and it also says one side of the spread hits in almost 60% of simulations! You ABSOLUTELY need to see it before locking in any college football picks.

So who wins Purdue vs. Syracuse? And which side of the spread hits almost 60% of the time? Join SportsLine now to find out, all from the model that has crushed its top-rated college football picks against the spread!