The Indiana Pacers and Detroit Pistons will begin their 2024-25 NBA seasons with a head-to-head matchup in Detroit on Wednesday night. The Pacers went to the Eastern Conference finals last season but where swept away by the eventual world champion Boston Celtics. Meanwhile, the Pistons went 14-68 to finish last in the East and tied the NBA record with a 28-game losing streak that lasted two months.

Tipoff from Little Caesars Arena in Detroit is set for 7 p.m. ET. The SportsLine consensus lists Indiana as the 5-point favorite in the latest Pistons vs. Pacers odds, while the over/under for total points scored is 235 (see up-to-date odds for every game this week on our NBA odds page). 

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