The Detroit Pistons and the Chicago Bulls are set to square off in a Central Division matchup at 7 p.m. ET on Oct. 20 at Little Caesars Arena. Chicago ended last season third in the Central Division at 31-41, while the Pistons finished fifth at 20-52. 

Chicago is favored by five points in the latest Pistons vs. Bulls odds from Caesars Sportsbook, and the over-under is set at 218.5. Before you make any Bulls vs. Pistons picks and predictions, you'll want to see what the SportsLine Projection Model is saying.

The SportsLine Projection Model simulates every NBA game 10,000 times and has returned almost $9,000 in profit on its top-rated NBA picks over the past three seasons. The model finished up almost $600 on its top-rated picks last season and enters the 2021-22 NBA season on a stunning 100-66 roll on top-rated NBA picks against the spread. Anyone following it has seen HUGE returns!

Now, it has simulated Pistons vs. Bulls 10,000 times and the results are in. We can tell you that the model is leaning Under, and it's also generated a point-spread pick that is hitting in over 60 percent of simulations. You absolutely need to see it before locking in your own picks.

So who wins Pistons vs. Bulls? And which side of the spread is a must-back? Join SportsLine right now to see which side of the spread you need to jump on, all from the computer model that has crushed its NBA picks... If you're already a member, see the picks below!