The West Virginia Mountaineers hit the road to kick off their season against the No. 7 Penn State Nittany Lions on Saturday night. West Virginia is coming off a disappointing 5-7 season in 2022, while Penn State is looking to build off its 11-2 season, which included a Rose Bowl victory, from a year ago. Kickoff is at 7:30 p.m. ET. The Nittany Lions are 20.5-point favorites in the latest Penn State vs. West Virginia odds, while the over/under is set at 52 points (see up-to-date odds for every game this week on our college football odds page).

Before making any West Virginia vs. Penn State picks, you NEED to check out the college football predictions from the SportsLine Projection Model.

The SportsLine Projection Model simulates every FBS college football game 10,000 times. Since its inception, the proprietary computer model has generated a stunning profit of almost $2,500 for $100 players on its top-rated college football picks against the spread. Anyone who has followed it has seen HUGE returns.

The model knows Penn State projects to have one of the most explosive offenses in the country in 2023. Led by Sophomore quarterback Drew Allar, the Nittany Lions are arguably as talented as any offensive group head coach James Franklin has had during his time in Happy Valley. 

The model also knows the Mountaineers are a much more complete team this year than they were in 2022. Sophomore running back CJ Donaldson Jr. has the ability to be one of the top running backs in the Big 12, and the WVU offensive line should be vastly improved.

Now, it has set its sights on Penn State vs. West Virginia. We can tell you the model is leaning Under on the point total, and it also says one side of the spread hits in well over 50% of simulations! You ABSOLUTELY need to see it before locking in any college football picks of your own.

Who wins Penn State vs. West Virginia, and which side of the spread hits in well over 50% of simulations? ... Join SportsLine right now to find out which side of the Penn State vs. WVU spread you should be all over Saturday, all from the model that's up almost $2,500 on top-rated CFB spread picks since its inception!