The No. 4 Penn State Nittany Lions begin a new Big Ten rivalry as they head out to face the USC Trojans on Saturday during the Week 7 college football schedule. The Nittany Lions are 5-0 and very much in the mix for a playoff spot, something that has eluded head coach James Franklin. USC has dropped two out of three and out of the Top 25, so head coach Lincoln Riley is feeling the heat as the Trojans adjust to life in the Big Ten.

Kickoff from LA Memorial Coliseum is at 3:30 p.m. ET on CBS and streamed live on Paramount+ (get a free 7-day trial). The Nittany Lions are 5.5-point favorites in the latest Penn State vs. USC odds, while the over/under for total points scored is 50.5 via SportsLine consensus.

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