The Penn State Nittany Lions will eye their third-straight win and second in a row on the road when they take on the Ohio State Buckeyes in Big Ten Conference play on Thursday. The Nittany Lions (16-11, 7-9 Big Ten), who are 2-7 on the road this season, are looking to win their second consecutive matchup against Ohio State, after defeating the Buckeyes (11-16, 3-13) 71-68 in the Big Ten Tournament at Indianapolis last March. Ohio State, meanwhile, has lost eight in a row and has fallen to 13th in the conference standings. This will be the only regular-season meeting between the teams.

The game from the Value City Arena in Columbus, Ohio, will tip off at 6:30 p.m. ET. The Buckeyes are 2-point favorites, according to the latest Penn State vs. Ohio State odds from Caesars Sportsbook, while the over/under for total points scored is set at 142.5 (see up-to-date odds for every game this week on our college basketball odds page).

Before making any Penn State vs. Ohio State picks, you NEED to check out the college basketball predictions from the SportsLine Projection Model.

The SportsLine Projection Model simulates every Division I college basketball game 10,000 times. The model enters Week 16 of the season 71-42 on all-top rated college basketball picks this season, returning more than $1,700 for $100 players. Anybody who has followed it has seen HUGE returns!

The model knows freshman forward Brice Sensabaugh leads the Buckeyes in scoring at 16.5 points per game, and is averaging 5.1 rebounds and one assist per game. He is also connecting on 48.2% of his field goals, including a blistering 43.5% from 3-point range, and 80.2% from the free-throw line. He is a three-time Big Ten Freshman of the Week, and has registered three double-doubles. He has nine games with 20 or more points, and is ranked fourth nationally in scoring among freshmen.

The model also knows Penn State senior guard Jalen Pickett has been red hot. The reigning National and Big Ten Conference Player of the Week scored 73 points and dished out 16 assists in the last two games. Pickett leads Penn State in scoring (18.6 points), rebounds (7.4) and assists (7.0), and is the only player in the country averaging 18 points and seven rebounds and assists. He is also connecting on 52.3% of his field goals, including 37.8% from 3-point range, and 80.3% from the foul line.

Now, it has set its sights on Penn State vs. Ohio State. It is leaning Over on the total and it also says one side of the spread hits more than 50% of the time! You ABSOLUTELY need to see it before locking in any college basketball picks.

Who wins Penn State vs. Ohio State? And which side of the spread hits more than 50% of the time? ... Join SportsLine right now to find out which side of the Penn State vs. Ohio State spread you should be all over Thursday, all from the model on a roll on college basketball picks!