The Carolina Panthers (0-1) will visit the New York Giants (1-0) on Sunday during the Week 2 NFL schedule. Kickoff is set for 1 p.m. ET from MetLife Stadium. New York is a 2-point favorite in the latest Panthers vs. Giants odds from Caesars Sportsbook, and the over/under for total points scored is 43.5. 

Before you make any Panthers vs. Giants picks of your own, you NEED to check out the NFL predictions from the SportsLine Projection Model.

The model, which simulates every NFL game 10,000 times, is up more than $7,500 for $100 players on top-rated NFL picks since its inception. The model enters Week 2 of the 2022 NFL season on an incredible 139-98 run on top-rated NFL picks that dates back to the 2017 season.

The model also ranked in the top 10 on NFLPickWatch four of the past six years on straight-up NFL picks and beat more than 94% of CBS Sports Football Pick'em players four times during that span. Anyone who has followed it is way up.

The model knows New York running Saquon Barkley is looking to bounce back after an injury-riddled 2021 campaign. Barkley is a dynamic weapon that can make an impact on the ground and through the air. The Penn State product has blazing speed, barreling strength, and sure hands. In the Week 1 win over the Tennessee Titans, Barkley logged 194 total yards with a score and the go-ahead 2-point conversion. 

The model also knows Carolina receiver Robbie Anderson is a deep threat for this aerial attack. Anderson is explosive with an outstanding ability to track down deep passes. The Temple product can easily separate from defenders due to his lightning-quick speed. In the season opener, Anderson led the team with five catches for 102 yards and a touchdown. 

Now, it has set its sights on Panthers vs. Giants. We can tell you the model is leaning Under the total, and it also says one side of the spread hits in well over 50% of simulations! You ABSOLUTELY need to see it before locking in any NFL picks.

So who wins Panthers vs. Giants? And which side of the spread cashes well over 50% of the time? Join SportsLine now to find out, all from the model that has crushed its top-rated NFL picks against the spread!