One of the most bitter rivalries in college football is on tap when the No. 8 Oregon Ducks (5-0) take on the No. 7 Washington Huskies (5-0) on Saturday at Husky Stadium in Seattle. Kickoff is at 3:30 p.m. ET. Both teams are coming off bye weeks. The Ducks dominated Stanford 42-6 in their last outing, while Washington defeated Arizona 31-24 on Sept. 30. The winner of this game will have an inside track at landing a spot in the Pac-12 Championship Game and potentially the College Football Playoff. Washington leads the all-time series 61–48–5 and won last year's matchup in Eugene 37-34.

The Huskies are 3-point favorites in the latest Oregon vs. Washington odds via SportsLine consensus, while the over/under for total points scored is 67, and Washington is a -159 favorite (risk $159 to win $100) on the money line (see up-to-date odds for every game this week on our college football odds page).

Before you make any Washington vs. Oregon picks or any other college football predictions, you NEED to see which side proven SportsLine expert Jimmie Kaylor is on. 

Kaylor is a NFL, college football, and DFS expert for SportsLine, who has covered the NFL and college football for close to a decade as a member of the Pro Football Writers of America. His background as a former college football All-American and NFL player gives him a unique perspective when building his fantasy lineups and locking in his betting picks. He has his finger on the pulse of the college football landscape and has been cashing in big for the last two years. 

Kaylor has been red-hot on his football picks for SportsLine in 2023, going 19-6 on his best bets up to this point in the season. Anyone who has followed his picks is WAY UP!

Kaylor knows that this Oregon team is far more physical -- especially on the defensive side of the ball -- than past teams. The Ducks rank sixth in the country in both total defense allowing 256.6 total yards and 11.8 points per game. Quarterback Bo Nix is a Heisman Trophy candidate and leads an Oregon offense that ranks second in the country in both total offense (557.8 yards per game) and points (51.6) per game.

Kaylor, however, also factored in that Washington has a Heisman contender of its own in Michael Penix Jr.. The Huskies rank first in college football in total offense (569.4 yards) and third in points scored (46.0) per game. Washington went into Autzen Stadium last year as 12-point underdogs and left with a 37-34 outright victory. 

Now, Kaylor has locked in a confident against-the-spread pick for Oregon vs. Washington. We can tell you he's leaning Under on the point total, but he knows a crucial X-factor makes one side of the spread a MUST-BACK! You ABSOLUTELY need to see what it is before locking in any picks of your own.

Who wins Oregon vs. Washington at Husky Stadium on Saturday, and what critical X-factor makes one side of the spread a must-back? ... Join SportsLine right now to see which side of the Washington vs. Oregon spread to jump on, all from the expert who is on a 19-6 roll this season, and find out!