The No. 12 Oregon Ducks (2-0) will take on the Brigham Young Cougars (2-0) at 10 p.m. ET on Tuesday, Nov. 16 in a highly intriguing early season college basketball matchup at Moda Center at the Rose Quarter in Portland. 

The Ducks are favored by 4.5 points in the latest Oregon vs. Brigham Young odds from Caesars Sportsbook, and the over-under is set at 141.5. Before you make any Brigham Young vs. Oregon picks and predictions, you'll want to see what the SportsLine Projection Model is saying.

The SportsLine Projection Model simulates every Division I college basketball game 10,000 times. Over the past five-plus years, the proprietary computer model has generated an impressive profit of almost $2,100 for $100 players on its top-rated college basketball picks against the spread. Anyone who has followed it has seen HUGE returns.

Now, it has simulated Oregon vs. Brigham Young 10,000 times and the results are in. We can tell you that the model is leaning Over, and it's also generated a point-spread pick that is hitting in almost 60 percent of simulations. You absolutely need to see it before locking in your own picks.

So who wins Oregon vs. Brigham Young? And which side of the spread is a must-back? Join SportsLine right now to see which side of the spread you need to jump on, all from the computer model that has crushed its college basketball picks... If you're already a member, see the picks below!