A Pac-12 matchup goes off between the Oregon State Beavers and the USC Trojans at 9:30 p.m. ET on Saturday at Reser Stadium. USC is undefeated under new head coach with Lincoln Riley with an offense that has looked unstoppable through its first three games. Meanwhile, Oregon State is playing like one of the most improved teams in the Pac-12 after a 3-0 start of its own, and is coming off of a win in which it dropped 68 points on Montana State last week. 

The Trojans are favored by six points in the latest Oregon State vs. USC odds from Caesars Sportsbook, and the over/under is set at 70.5. Before making any USC vs. Oregon State picks, you MUST see the college football predictions from the SportsLine Projection Model.

The SportsLine Projection Model simulates every FBS college football game 10,000 times. Over the past six-plus years, the proprietary computer model has generated a stunning profit of more than $3,300 for $100 players on its top-rated college football picks against the spread. It enters Week 4 of the 2022 college football season on a 51-43 run on all top-rated college football spread and money-line picks that dates back to 2021. Anyone who has followed it has seen HUGE returns!

Now, it has simulated Oregon State vs. USC 10,000 times and the results are in. We can tell you that the model is leaning Over, and it's also generated a point-spread pick that is hitting in nearly 70 percent of simulations. You absolutely NEED to see it before locking in your own picks!

Who wins Oregon State vs. USC? And which side of the spread is a must-back? Join SportsLine right now to see which side of the spread you need to jump on, all from the computer model that has crushed its college football picks.