No. 25 Oklahoma will be eyeing a signature victory when it hosts No. 6 Kansas in a Big 12 rematch in Norman. Tipoff is set for 4 p.m. ET on Saturday at Lloyd Noble Center. Kansas is favored by 2 points in the latest Oklahoma vs. Kansas odds, while the over/under is 143 points, per SportsLine consensus.

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The model has simulated Oklahoma vs. Kansas 10,000 times and the results are in. We can tell you that the model is leaning Over, and it's also generated a point-spread pick that is hitting in almost 70% of simulations. You can only see the pick at SportsLine.

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