The No. 5-ranked Houston Cougars will look to rebound from a tough loss at Kansas on Saturday when they meet the visiting Oklahoma State Cowboys in a key Big 12 matchup on Tuesday at 7 p.m. ET from the Fertitta Center in Houston. The Cowboys are 10-12 overall and 2-7 in the Big 12, while Houston is 19-3 and 6-3. Houston is favored by 21 points in the latest Oklahoma State vs. Houston odds, and the over/under is 128.5 points.

Before entering any Oklahoma State vs. Houston picks, you'll want to see the NCAA Basketball predictions from the model at SportsLine.

The model simulates every Division I college basketball game 10,000 times. It enters Week 14 of the 2023-24 season on a 124-82 roll on all top-rated college basketball picks dating back to last season, returning more than $2,000 for $100 players. It is also off to a sizzling 20-9 start on top-rated spread picks this season! Anyone following has seen HUGE returns.

The model knows senior L.J. Cryer, who is in his first season with the Cougars after three years at Baylor, is coming off a 24-point and three-assist performance in the loss at Kansas. It was the seventh time this season he surpassed 20 points. He also scored 23 points and grabbed four rebounds in a 75-68 win at BYU on Jan. 23. Cryer has scored in double digits in 16 of 22 starts this season.

It is also aware junior guard Javon Small, who played the last two seasons at East Carolina, has started all 21 games he has played in at Oklahoma State. He is coming off a solid effort in the win over Kansas State, scoring 18 points, dishing out seven assists and grabbing five rebounds. He registered a double-double in a 70-66 win over West Virginia on Jan. 27, scoring 15 points and grabbing 12 rebounds.

The model has simulated Oklahoma State vs. Houston 10,000 times and the results are in. We can tell you that the model is leaning Over, and it's also generated a point-spread pick that is hitting in well over 50% of simulations!

So who wins Oklahoma State vs. Houston, and which side of the spread hits well over 50% of the time! Join SportsLine right now to see which side of the spread you need to jump on, all from the computer model that is on a 20-9 roll on top-rated college basketball spread picks!