The Ohio Bobcats go on the road to take on the Louisiana Ragin' Cajuns. The Bobcats are coming off a two-point loss at home against Duquesne. The Ragin' Cajuns knocked off the Nicholls Colonels to secure their first win of the season. Louisiana is favored by 19.5 points in the latest odds from Caesars Sportsbook, while the Over-Under is set at 56.5 points. Kickoff from Lafayette, Louisiana is set for 8 p.m. ET. 

Before you make any Ohio vs. Louisiana picks, you'll want to see the college football predictions from the SportsLine Projection Model.