The Virginia Cavaliers will take on the Notre Dame Fighting Irish at 7:30 p.m. ET next Saturday in Scott Stadium. The Cavaliers are 6-3 overall and 4-1 at home, while Notre Dame is 8-1 overall and 2-0 on the road. The Fighting Irish are favored by 5.5 points in the latest Virginia vs. Notre Dame odds from Caesars Sportsbook, and the over-under is set at 64. Before you make any Notre Dame vs. Virginia picks, you'll want to see the college football predictions from the SportsLine Projection Model.

The SportsLine Projection Model simulates every FBS college football game 10,000 times. Over the past five-plus years, the proprietary computer model has generated a stunning profit of almost $3,500 for $100 players on its top-rated college football picks against the spread. It also enters Week 11 of the 2021 season on a 31-20 run on all top-rated college football side picks. Anyone who has followed it has seen huge returns.

Now, it has simulated Virginia vs. Notre Dame 10,000 times and the results are in. We can tell you that the model is leaning Under, and it's also generated a point-spread pick that is hitting in over 60 percent of simulations. You absolutely need to see it before locking in your own picks.

So who wins Virginia vs. Notre Dame? And which side of the spread is a must-back? Join SportsLine right now to see which side of the spread you need to jump on, all from the computer model that has crushed its college football picks... If you're already a member, see the picks below!