An ACC battle is on tap between the Notre Dame Fighting Irish and the Syracuse Orange at 7 p.m. ET Wednesday at Purcell Pavilion at the Joyce Center. Notre Dame is 19-8 overall and 11-1 at home, while 'Cuse is 15-12 overall and 3-6 on the road. The Fighting Irish are ranked second in the ACC; Syracuse is ranked seventh. 

The Fighting Irish are favored by five points in the latest Notre Dame vs. Syracuse odds from Caesars Sportsbook, and the over-under is set at 145.5. Before you make any Syracuse vs. Notre Dame picks and predictions, you'll want to see what the SportsLine Projection Model is saying.

The SportsLine Projection Model simulates every Division I college basketball game 10,000 times. Over the past five-plus years, the proprietary computer model has generated an impressive profit of almost $2,000 for $100 players on its top-rated college basketball picks against the spread. Anyone who has followed it has seen huge returns.

Now, it has simulated Notre Dame vs. Syracuse 10,000 times and the results are in. We can tell you that the model is leaning Over, and it's also generated a point-spread pick that is hitting in well over 50 percent of simulations. You absolutely need to see it before locking in your own picks.

So who wins Notre Dame vs. Syracuse? And which side of the spread is a must-back? Join SportsLine right now to see which side of the spread you need to jump on, all from the computer model that has crushed its college basketball picks... If you're already a member, see the picks below!