The Dallas Cowboys will look to stay hot when they square off against the Buffalo Bills on Sunday at Highmark Stadium in Orachard Park, N.Y. The Cowboys (10-3) have won five in a row and have overtaken the Eagles for first place in the NFC Esst. Meanwhile the Bills (7-6) are in a dogfight for one of the three wild card spots in the AFC. Kickoff is scheduled for 4:25 p.m. ET. Buffalo is a 1.5-point favorite in the latest Bills vs. Cowboys odds, while the over/under for total points scored is 50.5.

The game is one of 16 on the NFL schedule for Week 15, but which teams should you target with your NFL bets? Before you make any Week 15 NFL picks or NFL parlays, you need to see what SportsLine senior analyst Larry Hartstein has to say. 

A former lead writer for Covers and The Linemakers, Hartstein combines a vast network of Vegas sources with an analytical approach he honed working for Pro Football Focus. He tied for 52nd place (out of 1,598 entries) in the 2022 Westgate Las Vegas SuperContest, going 53-34-3 ATS. Those selections form the basis of his weekly SportsLine NFL best bets, which are 63-40-2 since the start of last season, including an 8-1 record the last three weeks.

Now, Hartstein has locked in three confident Week 15 NFL best bets. If you successfully parlay his picks, you're looking at a payout of almost 6-1.

We can tell you Hartstein loves the Bills to cover against the Cowboys. "The Cowboys play a ton of man coverage and that sets up well for Josh Allen's passing and scrambling," Hartstein told SportsLine.

Hartstein also has locked in two other confident Week 15 NFL picks, including one on a team with a defense that "shuts down the run." You ABSOLUTELY need to see his picks before betting on NFL Week 15.

So what are Hartstein's Week 15 NFL best bets? And what team that shuts down the run is a must-back? ... Join SportsLine right now to see Larry Hartstein's Week 15 NFL best bets, all from the expert who went 53-34-3 in the SuperContest last year!