After Week 6 of the 2021 NFL season, we'll be more than one-third of the way through the season. The results of your NFL office pool picks may paint a clear picture of who has this season figured out. There's still plenty of time to pad those leads or chase down the leaders, and having a winning NFL pick'em strategy could make or break the rest of the way.

Before making any Week 6 NFL pick'em predictions, you NEED to see which teams the SportsLine Projection Model is backing in its NFL football pool picks.

The model, which simulates every NFL game 10,000 times, is up almost $7,900 for $100 players on top-rated NFL picks since its inception six years ago. It went a sizzling 24-14 on top-rated NFL picks last season, returning more than $800. The model also enters the 2021 season on an incredible 125-83 run on top-rated NFL picks that dates back to the 2017 season.

More importantly for NFL confidence pool players, the model also ranked in the top 10 on NFLPickWatch four of the past five years on straight-up NFL picks and beat more than 94 percent of CBS Sports office pool players four times during that span. Anyone who has followed it is way up!

In Week 6, we can tell you the model is extremely high on the Indianapolis Colts beating the Houston Texans. In fact, the model is projecting a 12-point win for the Colts, who get up the straight-up victory in 80 percent of simulations.

The model has also identified multiple underdogs who win outright in Week 6. Picks like these can give you a HUGE edge in your pools. You ABSOLUTELY need to see which team the model is backing before locking in your NFL office pool picks!

So which teams win outright in Week 6? And which favorites go down hard? ... Join SportsLine right now to see the SportsLine Projection Model's office pool picks, all from the model that consistently crushes the NFL and has ranked in the top 10 on NFLPickWatch four of the past five years!