Week 4 of the 2023 NFL schedule is loaded with pivotal matchups, including Ravens vs. Browns (-2.5), Dolphins vs. Bills (-3), and Patriots vs. Cowboys (-6). The Week 4 NFL schedule wraps up on Monday Night Football with a matchup between the Seahawks and Giants (+1.5) in a game that has seen the favorite change several times already. Before making any Week 4 NFL office pool picks, you NEED to see which teams the SportsLine Projection Model is backing in its NFL football pool picks.

The model, which simulates every NFL game 10,000 times, is up well over $7,000 for $100 players on top-rated NFL picks since its inception. The model enters Week 4 of the 2023 NFL season on an incredible 167-117 run on top-rated NFL picks that dates back to the 2017 season. It is also on a 21-9 roll on top-rated NFL picks since Week 7 of last season.

The model also ranked in the top 10 on NFLPickWatch four of the past six years on straight-up NFL picks and beat more than 94% of CBS Sports Football Pick'em players four times during that span. Anyone who has followed it is WAY UP!

In Week 4, we can tell you the model is high on the San Francisco 49ers (-14) defeating the Arizona Cardinals at home. The model is projecting a 31-17 win for the 49ers, who secure the straight-up victory in over 80% of simulations. San Francisco is averaging 30.0 points per game this season, which ranks third in the NFL. Defensively, the 49ers are giving up just 53 rushing yards per game. The Cardinals, meanwhile, are just 1-6 in their last seven games on the road. 

The model has also locked in NFL picks for every Week 4 NFL game and says several favorites struggle BIG-TIME! You ABSOLUTELY need to see which teams the model is backing before locking in your NFL pool picks!

So which teams win outright in Week 4, and which favorites should you avoid? ... Join SportsLine right now to see the SportsLine Projection Model's office pool picks, all from the model that has returned over $7,000 on its top-rated NFL picks!